. . Aorticstenosis makes infective endocarditis, a severe infection of the heart lining and valves, more likely. It's caused by bacteria getting into your bloodstream -- even through your gums. To. . Aorticsclerosis is associated with systemic endothelial dysfunction, and a small percentage of cases may progress to aorticstenosis. Lowering of LDL cholesterol by 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors have been shown to decrease progression of aorticvalve calcification. Aorticsclerosis is not a mere benign. . Calcific aorticvalve disease is a slowly progressive disease that starts with mild fibrosis and calcification and thickening of the valve leaflets without obstruction of blood flow, which is termed aorticsclerosis .This disease evolves over the years to severe calcification with impaired leaflet mobility and significant obstruction to blood flow, i.e. aorticstenosis (AS). Calcific aorticstenosis is the most common indication for surgical valve replacement in the United States. 1 With the decline of acute rheumatic fever, calcific aorticstenosis has become the most common indication for valvular disease in the United States. Landmark epidemiological studies identified risk factors for the aorticvalve which are similar to those of vascular atherosclerosis.
. . ing and calcification of aorticvalve leaflets, i.e., aorticvalvesclerosis, which leads to reduction of valve opening and obstruction to left ventric- ular (LV) outflow . Surgery for Asymptomatic AorticValveStenosis * Surgery is not traditionally considered for the asymptomatic patient, regardless the degree of stenosis, because the risk of sudden death is considered to be low (estimated at<1%/year), and the risk of the AVR may exceed the potential benefit of surgery.; Severe AS need to be followed carefully for the development of symptoms or rapidly. . . A doctor may suspect aorticvalvesclerosis on hearing a heart murmur with a stethoscope. However, an ultrasound of the heart (echocardiogram) can distinguish between aorticvalvesclerosis and stenosis and check for other possible causes of a heart murmur. Calcified valve leaflets can also impact each of the other valves within the heart - the. .
The prevalence of aorticstenosis in the population older than 65 years is 2% to 7%; aorticsclerosis, the precursor to aorticstenosis in which there is valve thickening but no stenosis, is present in approximately 25% of this age group. 2, 3 Whereas aorticstenosis is seen in patients with both tricuspid and bicuspid aorticvalves, the. If a valve doesn't fully open or close, blood flow is reduced or blocked. In aorticvalvestenosis, the aorticvalve between the lower left heart chamber (left ventricle) and the aorta does not open completely. The area through which blood moves out of the heart to the aorta is narrowed (stenosis). . . Aorticsclerosis is a degenerative aorticvalve disease with thickening of aorticvalve structures by fibrosis and calcification initially without causing significant obstruction. Over years, aorticsclerosis progresses to stenosis in as many as 15% of patients. . . .